Genes VII, the latest edition of this well-respected and best-selling textbook covers the material that is at the core of current courses in molecular biology, genetics, cell biology, and related disciplines. It gives an integrated and authoritative account of the structure and function of genes and is thoroughally up-to-date with the latest research and thinking in the field. In a change to the approach of all previous editions, which started with a traditional analysis of formal genetics, this seventh edition has been organised to present the subject in the context of the eukaryotic gene as revealed in the last decade, an analysis based directly on the molecular properties of the gene itself. This new approach has made the book more concise, and the smart new design presents the material refreshingly clearly. Contents Part 1 Genes 1 Genes are DNA 2 From genes to genomes 3 How many genes are there? 4 Clusters and repeats Part 2 Proteins 5 Messenger DNA 6 Protein Synthesis 7 Interpreting the genetic code 8 Protein localization Part 3 mRNA 9 Transcription 10 The operon 11 Phage strategies Part 4 DNA 12 The replicon 13 DNA replication 14 Recombination and repair 15 Transposons 16 Retroviruses and retroposons 17 Rearrangement of DNA Part 5 The nucleus 18 Chromosomes 19 Nucleosomes 20 Initiation of transcription 21 Regualtion of transcription 22 Nuclear splicing 23 Catalytic RNA 24 Immune diversity Part 6 Cells 25 Protein trafficking 26 Signal transduction 27 Cell cycle and growth regualtion 28 Oncogenes and cancer 29 Gradients and cascades