An all-new epic adventure teaming the classic Earth's Mightiest Heroes with Marvel's premiere Non-Team! A strange and impossible lost memory from his days in World War II draws Namor the Sub-Mariner to his onetime compatriot Captain America - but the two heroes and their respective allies find themselves pulled into a labyrinth of pain, destruction and madness courtesy of the Infernal Ichor of Ish'lzog! It's Avenger vs. Defender as the alchemist Diablo casts another card from the deck of fate, pitting hero against hero for his own nefarious purposes!