It's 1926 and reapers, the once-human vampires with a terrifying affliction, are on the rise in New York. But the Saint family's thriving reaper-hunting enterprise holds reign over the city, giving them more power than even the organized criminals who run the nightclubs. Eighteen year-old Elise Saint, home after five years in Paris, is the reluctant heir to the empire. Only one thing weighs heavier on Elise's mind than her family obligations: the knowledge that the Harlem reapers want her dead. Layla Quinn is a young reaper haunted by her past. When Layla is framed for one of these attacks, she must work with Elise to investigate these murders.