A historic cruise ship, a haunted ship, the Celtic American Line's Destiny, sets sail from the Port of New Orleans, with a killer on board. He's known as the Archangel Killer because of the way he displays his victims in churches. And how he places a different saint's medallion on each body. No one knows exactly who he is or why he's doing this. Jackson Crow, head of the FBI's Krewe of Hunters, a special unit of paranormal investigators, is assigned to the case, along with local agent Jude McCoy. Then Alexi Cromwell, who works in the ship's piano bar, is drawn into the situation when a victim's ghost appears to her, and to Jude. She and Jude share an attraction, and not just because of their mutual talent.